Description

TB-500 (Thymosin Beta-4) 5mg – Research Peptide

TB-500, a synthetic version of the naturally occurring protein Thymosin Beta-4, is a 43-amino acid peptide with remarkable regenerative potential. It’s widely researched for its role in promoting tissue repair, enhancing recovery, and reducing inflammation and oxidative stress in various systems of the body, including the nervous and cardiovascular systems.

What Is TB-500?

TB-500 is the lab-made counterpart of Thymosin Beta-4, which is found in almost all human and animal cells. This peptide has been shown in laboratory settings to support wound healing, stimulate blood vessel formation, regulate inflammation, and aid in tissue repair. Much of its action revolves around its interaction with actin—a vital protein involved in cell structure and movement.

Due to these powerful regenerative properties, TB-500 has become a key focus in scientific research related to injury recovery, cardiovascular health, neurodegenerative diseases, and even anti-aging strategies.

How TB-500 Works

The mechanism of TB-500 revolves around actin binding. Actin is crucial for maintaining cell shape, allowing cells to move, divide, and form muscle fibers. TB-500 helps preserve and mobilize actin, supporting tissue regeneration and cellular repair. This function makes it a central player in healing damaged tissues and promoting structural cell integrity across multiple body systems.

Peptide Details

• Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser

• Molecular Formula: C212H350N56O78S

• Molar Mass: 4963.44 g/mol

• CAS Number: 77581-33-4

• PubChem ID: 16132341

Areas of Scientific Research

1. Nervous System Repair

Studies in animal models suggest that TB-500 promotes healing in the brain and spinal cord by supporting cells that nourish and protect neurons. This can lead to improved recovery after injury and enhanced brain function.

2. Blood Vessel Formation

TB-500 plays a key role in blood vessel development. It stimulates VEGF (vascular endothelial growth factor), which is essential for capillary growth—important for wound healing, tissue oxygenation, and even hair growth.

3. Hair Growth

Researchers found that mice with higher levels of Thymosin Beta-4 regrew hair faster. These mice showed more hair follicles and healthier hair growth—paving the way for further study in hair restoration research.

4. Antibiotic Support

When combined with antibiotics like ciprofloxacin, TB-500 enhanced their effectiveness in animal studies, reducing infection severity and improving healing outcomes. This may offer a future path in fighting antibiotic-resistant infections.

5. Cardiovascular Benefits

Research indicates TB-500 may help the heart by encouraging new blood vessel growth, improving cell survival after a heart attack, and reducing fibrosis (scar tissue). It’s even being studied in combination with collagen-based hydrogels for heart tissue regeneration.

6. Neurodegenerative Disease Potential

Early studies suggest that TB-500 might enhance the brain’s natural cleaning process, known as autophagy. This could offer hope for conditions like Alzheimer’s or prion disease by boosting the body’s ability to eliminate harmful proteins.

7. Wide Range of Applications

Due to its foundational role in cellular structure and regeneration, TB-500 is being researched for a broad spectrum of uses—from tissue repair and immune modulation to improving recovery from major trauma and chronic conditions.

Research Use Only

TB-500 is intended strictly for scientific research and laboratory use only. It is not approved for human or veterinary use. Any mention of potential applications is based solely on preclinical studies.