Description

Semax 30mg – Cognitive & Neuroprotective Peptide

Semax is a synthetic peptide originally developed in Russia as a derivative of adrenocorticotropic hormone (ACTH). It has gained significant attention in research circles for its potential neuroprotective, cognitive-enhancing, and immune-modulating effects. Semax may help support brain function, improve recovery after neurological trauma, and even enhance mood regulation.

What is Semax?

Semax is a lab-engineered fragment of the ACTH molecule, specifically focusing on amino acids 4–10. Its design allows it to interact with the central nervous system without influencing cortisol levels, setting it apart from its parent hormone. Research suggests that Semax increases levels of brain-derived neurotrophic factor (BDNF), dopamine, and serotonin—all of which are vital for mood, memory, and overall brain health.

Potential Benefits of Semax (Based on Research)

• Supports Cognitive Performance By increasing BDNF and improving communication between brain regions, Semax may help boost learning, memory, focus, and overall mental clarity.

• Neuroprotection During Stroke Recovery In Russian clinical settings, Semax is used during stroke rehabilitation. Studies suggest it may help protect neurons, promote blood vessel formation in the brain, and speed up functional recovery.

• Mood and Mental Health Support Semax may offer antidepressant and anxiolytic (anti-anxiety) effects. Its ability to elevate BDNF could play a role in balancing mood and improving emotional resilience.

• Enhances Brain Connectivity Functional imaging studies show that Semax activates the brain’s “default mode network,” which is essential for social cognition and mental readiness when transitioning from rest to task engagement.

How Semax Works

Semax interacts with the brain in several ways. It appears to:

• Increase BDNF and NGF (nerve growth factor) expression

• Stimulate gene activity in regions associated with learning and memory, like the hippocampus and frontal cortex

• Activate the brain’s resting-state network to boost awareness and cognitive flexibility

• Encourage neuroplasticity, making it easier for the brain to adapt or recover after damage

These mechanisms make it a promising candidate for addressing cognitive decline, brain injuries, and mood disorders.

Research on Stroke & Brain Injury

Animal and human studies conducted in Russia highlight Semax’s role in supporting recovery from cerebral hypoxia and stroke. It has been shown to trigger the expression of multiple genes related to vascular function, neuroprotection, and energy metabolism in the brain. These effects may help preserve neurons, improve blood flow, and enhance brain energy levels during and after traumatic brain events.

Semax and Learning Enhancement

The cognitive effects of Semax are not limited to injury settings. Research suggests that even in healthy subjects, Semax may enhance memory retention, learning capacity, and information processing. This makes it a topic of interest in the field of nootropics—substances that support mental performance.

Semax in Mental Health Research

Studies in animal models indicate that Semax may help alleviate symptoms of depression by increasing BDNF levels. While traditional antidepressants like SSRIs take weeks to produce noticeable effects, Semax’s more direct influence on neurogenesis and neurotransmitter balance could offer a faster route to mental wellness—pending further research.

Scientific Profile

• Sequence: Ac-Met-Glu-His-Phe-Pro-Gly-Pro

• Molecular Formula: C37H51N9O10S

• Molecular Weight: 854.99 g/mol

• CAS Number: 80714-61-0

• Synonyms: Pro-Gly-Pro-ACTH

Important Notice

This product is intended for educational and scientific research purposes only. It is not approved for human or veterinary use. Any in-vivo applications are strictly prohibited unless you are a licensed researcher working under regulated laboratory conditions.