Description
Follistatin 315 1mg – Powerful Myostatin Inhibitor & Inflammation Modulator
What Is Follistatin 315?
Follistatin 315 is a naturally occurring protein best known for its role in muscle growth and repair. It’s one of the key isoforms of follistatin found abundantly in blood plasma. This powerful glycoprotein binds and neutralizes activin and myostatin—two proteins that limit muscle growth and contribute to inflammation. By blocking them, Follistatin 315 promotes increased muscle mass, improved fertility, and may help reduce inflammatory responses.
How It Works
Follistatin 315 binds to myostatin, a protein that restricts muscle growth. By suppressing this pathway, it encourages both hypertrophy (muscle enlargement) and hyperplasia (new muscle cell formation). It also plays a role in:
-
Reducing inflammation
-
Supporting blood vessel formation
-
Protecting against muscle-wasting conditions
-
Improving tissue repair
-
Enhancing fertility and embryonic development
Follistatin 315 and Muscle Growth
One of the most exciting aspects of Follistatin 315 is its ability to enhance muscle development. In lab studies, mice engineered to overproduce follistatin had up to four times more muscle mass than normal mice. This was even more dramatic when combined with the inhibition of myostatin, resulting in what’s famously called the “mighty mouse.”
This dual-action—blocking myostatin and promoting muscle growth independently—suggests multiple pathways through which Follistatin 315 supports muscle development.
Research in Muscle-Wasting Diseases
Studies in animal models of spinal muscular atrophy (SMA) show that Follistatin 315 not only helps retain muscle mass but also improves nerve cell health and extends lifespan. Similarly, in monkeys with inclusion body myositis, follistatin administration resulted in noticeable muscle improvement.
Anti-Inflammatory Potential
Follistatin 315 also shows promise as an anti-inflammatory agent. Research in arthritis and asthma models has demonstrated that supplementing with follistatin helps reduce inflammation and prevent tissue damage. In asthma, it helped prevent airway remodeling—a key contributor to disease progression.
Its ability to regulate inflammation could extend to other conditions, such as lung fibrosis, transplant complications, and autoimmune diseases.
Supporting Tissue Repair and Vascular Health
Follistatin has shown the ability to enhance blood vessel growth in response to injury. This could have wide-ranging applications—from improving recovery after heart attacks or strokes to supporting muscle repair, burn healing, and post-surgical recovery.
Kidney and Cardiovascular Health
Emerging research indicates that Follistatin 315 may slow the progression of chronic kidney disease by reducing oxidative stress, inflammation, and tissue scarring. In cardiovascular health, elevated follistatin levels have been linked to early signs of disease, suggesting its potential use as a diagnostic marker or even a treatment to improve heart function.
A Model for Protein-Based Therapy
Follistatin 315 is not just a promising compound—it’s helping shape the future of therapeutic protein development. Scientists are exploring modified versions to increase its effectiveness and stability, paving the way for targeted treatments across multiple medical fields.
Key Details
-
Synonyms: Activin-Binding Protein, FST, FSH-Suppressing Protein
-
Molecular Weight: 3470 g/mol
-
Structure: 344-amino-acid glycoprotein
-
PubChem CID: 178101631
Important Note
Follistatin 315 is intended for scientific research and educational purposes only. It is not approved for human or veterinary use. This product must only be handled by qualified professionals in controlled laboratory environments.





Reviews
There are no reviews yet.