Description
Hexarelin: The Peptide for Heart and Muscle Protection
Hexarelin is a synthetic peptide that is closely related to ghrelin, a hormone involved in various bodily functions. It has gained attention for its beneficial effects on heart health, muscle preservation, and fat regulation. Hexarelin has been heavily researched for its potential to protect the heart from damage following a heart attack and for its ability to support muscle health during conditions such as muscle wasting and cachexia.
What Is Hexarelin?
Hexarelin, also known as Examorelin, is a synthetic analogue of ghrelin, a hormone that plays a crucial role in regulating hunger and metabolism. It shares a close relationship with GHRP-6, differing only by two added methyl groups. This peptide has been studied extensively for its potential to improve heart health, protect muscles from wasting, and regulate lipid levels.
Hexarelin is typically administered subcutaneously, showing excellent bioavailability, making it a valuable research tool for scientists studying its impacts on heart cells, muscle tissue, and metabolic health.
Key Benefits of Hexarelin
1. Heart Health Support
Hexarelin is known for its ability to support heart health, particularly in the aftermath of a heart attack. Research indicates that Hexarelin helps prevent heart cells from undergoing apoptosis (programmed cell death) by binding to the CD36 receptor and the growth hormone secretagogue receptor (GHSR). In studies with mice, Hexarelin improved heart function, promoted the survival of heart cells, and reduced markers of heart cell death, leading to a healthier heart following ischemic injury.
2. Muscle Protection and Preservation
Hexarelin doesn’t just benefit the heart—it also plays a significant role in muscle protection. In animal studies, it has been shown to protect skeletal muscle against wasting, particularly in cases of extreme weight loss due to illness or chemotherapy. The peptide helps regulate calcium flow and mitochondrial function, both crucial for maintaining muscle integrity and energy production. These benefits make Hexarelin valuable for those at risk of muscle loss due to various conditions.
3. Cholesterol and Triglyceride Regulation
Hexarelin has shown promise in improving lipid profiles, particularly in managing dyslipidemia, an imbalance of fats in the blood that can lead to diabetes. In animal models, Hexarelin helped reduce both blood sugar levels and insulin resistance while simultaneously correcting lipid imbalances. These effects suggest that Hexarelin may offer a new approach for managing conditions associated with metabolic syndrome and cardiovascular risk.
Hexarelin: A Promising Peptide for Research
Hexarelin has been extensively researched for its potential in treating heart disease, muscle wasting, and metabolic disorders. Its ability to improve heart cell survival, regulate fat metabolism, and protect muscle tissue opens up new possibilities for managing conditions that are currently difficult to treat.
While Hexarelin shows great promise, it is important to note that it is intended for scientific research purposes only and is not approved for human consumption. Researchers interested in studying Hexarelin can access it for educational and research purposes to further explore its therapeutic potential.
Hexarelin Structure
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Sequence: His-D-Trp(2-Me)-Ala-Trp-D-Phe-Lys
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Molecular Formula: C47H58N12O6
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Molecular Weight: 887.000 g/mol
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PubChem CID: 6918297
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CAB Number: 140703-51-1
Hexarelin’s ability to influence various biological processes makes it a valuable peptide for advancing scientific knowledge, particularly in cardiovascular and metabolic research. As research continues, Hexarelin could potentially offer new insights into managing heart disease and related conditions.





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